Reactive hemophagocytosis in systemic lupus erythematosus.
Reactive hemophagocytosis in systemic lupus erythematosus.
复制标题
系统性红斑狼疮的反应性噬血细胞作用。
DOI：
10.2169/internalmedicine.37.550
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发表时间：
1998
影响因子：
1.2
通讯作者：
S. Kobayashi
中科院分区：
文献类型：
--
作者：
K. Takahashi;S. Kumakura;H. Ishikura;Y. Murakawa;Y. Yamauchi;S. Kobayashi
系统性红斑狼疮（SLE）患者发生反应性噬血细胞症。该病例除SLE本身外，未显示任何基础疾病，如感染或恶性肿瘤。在SLE中诱导噬血细胞作用的机制似乎是异质的，仍有待阐明。虽然免疫复合物介导的机制在急性狼疮噬血细胞综合征的情况下已被提出，我们建议IL-1 β作为我们的病例的发病机制可能参与。
A patient with systemic lupus erythematosus (SLE) developed reactive hemophagocytosis. This case did not show any underlying diseases such as infection or malignancy other than SLE itself. The mechanisms inducing hemophagocytosis in SLE seem to be heterogeneous and remain to be elucidated. Although an immune complex-mediated mechanism in cases with acute lupus hemophagocytic syndrome has been proposed, we suggest the possible involvement of IL-1beta as the pathogenesis of our case.