Inactivation of influenza virus by solar radiation
Inactivation of influenza virus by solar radiation
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DOI：
10.1111/j.1751-1097.2007.00177.x
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发表时间：
2007-09-01
影响因子：
3.3
通讯作者：
Lytle, C. David
中科院分区：
文献类型：
--
作者：
Sagripanti, Jose-Luis;Lytle, C. David
流感病毒很容易通过气溶胶传播，其在环境中的灭活可能有助于限制流感流行的传播。阳光中的紫外线辐射是环境中的主要杀病毒剂，但流感病毒在受感染宿主体外保持传染性的时间仍有待确定。在这项研究中，我们计算了世界多个城市在一年中不同时间太阳紫外线辐射对甲型流感病毒的预期灭活情况。这里报告的灭活率表明，在许多温带城市的冬季“流感季节”，甲型流感病毒颗粒从宿主释放几天后仍具有传染性，并且存在重新雾化和人类感染的持续风险。低和高太阳病毒辐射与高和低疾病患病率之间的相关性表明，太阳紫外线辐射对环境中病毒的灭活在流感大流行的季节性发生中发挥了作用。
Influenza virus is readily transmitted by aerosols and its inactivation in the environment could play a role in limiting the spread of influenza epidemics. Ultraviolet radiation in sunlight is the primary virucidal agent in the environment but the time that influenza virus remains infectious outside its infected host remains to be established. In this study, we calculated the expected inactivation of influenza A virus by solar ultraviolet radiation in several cities of the world during different times of the year. The inactivation rates reported here indicate that influenza A virions should remain infectious after release from the host for several days during the winter "flu season" in many temperate-zone cities, with continued risk for reaerosolization and human infection. The correlation between low and high solar virucidal radiation and high and low disease prevalence, respectively, suggest that inactivation of viruses in the environment by solar UV radiation plays a role in the seasonal occurrence of influenza pandemics.