Oligoarene Strategy for Catalyst Development. Hydroxylated Oligoarene‐Type Phosphines for Palladium‐Catalyzed Cross Coupling.
Oligoarene Strategy for Catalyst Development. Hydroxylated Oligoarene‐Type Phosphines for Palladium‐Catalyzed Cross Coupling.
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用于钯催化交叉偶联的羟基化低聚芳烃型膦催化剂开发策略。
DOI：
10.1002/chin.200814051
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
K. Manabe
中科院分区：
文献类型：
--
作者：
S. Ishikawa;K. Manabe
基于我们开发的两步重复方法合成了各种具有羟基的寡芳烃型膦，并且这些膦被用作与格氏试剂催化交叉偶联的钯的配体。研究表明，羟基化三苯膦加速了邻溴苯酚的交叉偶联速率，并表现出邻位异构体优于Meta位和对位异构体的倾向。
Various oligoarene-type phosphines having a hydroxy group were synthesized based on a two-step repetitive method that we developed, and these phosphines were used as ligands for palladium in catalytic cross coupling with Grignard reagents. The study revealed that a hydroxylated terphenylphosphine accelerated the rate of the cross coupling ofo-bromophenol and exhibited preference for the ortho-isomer over the meta- and para-isomers.