Poor oral intake causes enteral nutrition dependency after concomitant chemoradiotherapy for pharyngeal cancers.
Poor oral intake causes enteral nutrition dependency after concomitant chemoradiotherapy for pharyngeal cancers.
复制标题
咽癌同步放化疗后，口服摄入不足会导致肠内营养依赖。
DOI：
10.1007/s00405-018-4963-y
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Katori Y.
中科院分区：
文献类型：
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作者：
Ishii R;Kato K;Ogawa T;Sato T;Nakanome A;Ohkoshi A;Kawamoto-Hirano A;Shirakura M;Hidaka H;Katori Y.
目的探讨头颈部肿瘤同期放化疗(CCRT)后肠内营养(EN)依赖的诱发因素及其统计学相关性。方法对26例确诊接受CCRT的口咽癌和下咽癌患者的进食情况、营养状况、疾病和治疗等因素进行回顾性调查。以住院期间无口服进食天数(NOI)和CCRT后肠内营养使用天数为喂养状况，以体重变化反映营养状况。结果总噪声指数(≥ )持续时间长( ≥ 30d)和最大噪声指数(NOI)14d是EN依赖的显著预测因素。体重下降(≥ 7.5g)是下一个确定的预测因素，但不显著。多因素分析显示，持续时间长的NOI与EN依赖的相关性大于体重变化。结论长期NOI与EN依赖的相关性大于营养因素。
PurposeTo identify precipitating factors responsible for enteral nutrition (EN) dependency after concomitant chemoradiotherapy (CCRT) of head and neck cancers and to examine their statistical correlations.MethodsFactors related to feeding condition, nutritional status, disease, and treatment of 26 oropharyngeal and hypopharyngeal cancer patients who received definitive CCRT were retrospectively investigated by examining their medical records. The days of no oral intake (NOI) during hospitalization and the months using enteral nutrition after CCRT were counted as representing the feeding condition, and the changes in body weight (BW) were examined as reflecting nutritional status. The factors related to EN dependency after CCRT were analyzed.ResultsLong duration of total NOI (≥ 30 days) and maximum NOI ≥ 14 days were significant predictors of EN dependency. Decreased BW (≥ 7.5 kg) was the next predictor identified, but it was not significant. Multivariate analysis showed that the total duration of NOI was more correlated with EN dependency than changes in BW.ConclusionsA long duration of NOI was more strongly related to EN dependency than nutritional factors.