ATYPICAL FORM OF RETINOPATHY OF PREMATURITY WITH SEVERE FIBROVASCULAR PROLIFERATION IN THE OPTIC DISC REGION
ATYPICAL FORM OF RETINOPATHY OF PREMATURITY WITH SEVERE FIBROVASCULAR PROLIFERATION IN THE OPTIC DISC REGION
复制标题
视盘区域严重纤维血管增生的非典型早产儿视网膜病
DOI：
10.1097/iae.0000000000001779
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Azuma N
中科院分区：
文献类型：
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作者：
Yokoi T;Katagiri S;Hiraoka M;Nakayama Y;Hosono K;Hotta Y;Nishina S;Azuma N
目的：描述早产儿视网膜病变（ROP）非典型形式中视盘区域发生的严重纤维血管增生。方法：回顾性观察病例报告。结果：纳入4例（8只眼）早产儿视网膜病变患者。3例患者非常早产（胎龄24-25周;体重500- 1，000克）; 1例患者在胎龄33周时出生。4例患者的8只眼均接受了ROP筛查并接受了激光光凝，其中6只眼主要在视盘区有不典型和严重的纤维血管增生;另外2只眼，包括1只眼经典型ROP和1只眼侵袭性后房型ROP，没有不典型的形式。所有8只眼睛都有完全或部分视网膜脱离。在6只非典型形式的眼睛中，3只眼睛可以进行早期玻璃体手术和晶状体切除术; 2只眼睛只能进行晚期玻璃体手术和晶状体切除术; 1只眼睛无法手术。3只眼部分或完全复位，3只眼完全视网膜脱离。在6只患眼中，只有2只患眼获得了光感view.Conclusion：一种不典型的严重形式的ROP，其中纤维血管增生主要来自视盘区域，除了激光光凝和玻璃体手术外，还需要进一步研究治疗。
Purpose:To describe severe fibrovascular proliferation that developed in the optic disk region in an atypical form of retinopathy of prematurity (ROP).Methods:Retrospective observational case reports.Results:Four patients (8 eyes) with ROP were included. Three patients were born very prematurely (24–25 weeks of gestational age; weight, 500–1,000 grams); 1 patient was born at 33 weeks of gestational age. Among all eight eyes of four patients who received prompt ROP screening and underwent laser photocoagulation, six eyes had atypical and severe fibrovascular proliferation mainly in the optic disk region; the other two eyes, including one eye with classic ROP and one eye with aggressive posterior ROP, did not have the atypical form. All eight eyes had a total to partial retinal detachment. Among the six eyes with the atypical form, early vitreous surgery with lensectomy was possible in three eyes; only late vitreous surgery with lensectomy was possible in two eyes; one eye was inoperable. Three eyes had a partial or complete reattachment, whereas three eyes had a total retinal detachment. Among the six eyes with atypical fibrovascular proliferation, only two eyes obtained light perception vision.Conclusion:An atypical and severe form of ROP, in which fibrovascular proliferation grew mainly from the optic disk region, needs further investigation for treatment in addition to laser photocoagulation and vitreous surgery.