Suzuki cross-coupling reaction of aryl and heterocyclic bromides and aromatic polybromides on a Pd(II)-hydrotalcite catalyst
Suzuki cross-coupling reaction of aryl and heterocyclic bromides and aromatic polybromides on a Pd(II)-hydrotalcite catalyst
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DOI：
10.1002/aoc.1359
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发表时间：
2008-02
影响因子：
3.9
通讯作者：
M. Mora;C. Jiménez-Sanchidrián;J. Ruiz
中科院分区：
文献类型：
--
作者：
M. Mora;C. Jiménez-Sanchidrián;J. Ruiz
研究了以碳酸钾为碱，90 °C下，在MgAl水滑石负载Pd（AcO）2 Py 2催化剂上，不同含溴底物与苯硼酸在甲苯中的Suzuki偶联反应.对于许多底物获得的转化率和选择性结果是优异的，并且类似于由更活性或甚至均相催化剂提供的那些。芳基多溴和苯基硼酸的反应得到了相应的聚芳族化合物的可变产率取决于特定的底物。通过取代不同的Br原子，以连续的方式发生芳基化。在反应之前和之后进行的催化剂的钯含量的ICP-MS测量显示，部分金属被并入本体溶液中;因此，催化过程不是纯粹的多相的。版权所有© 2008约翰威利父子有限公司。
The Suzuki cross-coupling reaction of various bromine-containing substrates and phenylboronic acid in toluene at 90 °C on a Pd(AcO)2Py2 catalyst supported on an MgAl hydrotalcite, using K2CO3 as the base, was studied. The conversion and selectivity results obtained for many of the substrates were excellent and similar to those provided by more active or even homogeneous catalysts. The reactions of aryl polybromides and phenylboronic acid gave the corresponding polyaromatic compounds in variable yields depending on the particular substrate. Arylation occurred in a consecutive manner by substitution of the different Br atoms. ICP-MS measurements of the palladium content of the catalyst performed prior to and after the reaction revealed that part of the metal is incorporated into the bulk solution; therefore, the catalytic process is not purely heterogeneous. Copyright © 2008 John Wiley & Sons, Ltd.