Properties, chemistry, and applications of the bioactive polysaccharide curdlan.
Properties, chemistry, and applications of the bioactive polysaccharide curdlan.
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DOI：
10.1021/bm500038g
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发表时间：
2014-03
影响因子：
6.2
通讯作者：
Ruoran Zhang;K. Edgar
中科院分区：
文献类型：
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作者：
Ruoran Zhang;K. Edgar
可得然胶是一种细菌多糖，由于其有趣和有价值的流变学性质及其固有的生物活性，最近引起了人们的极大兴趣。相对于许多其他丰富的天然多糖，可得然胶的简单（1→3）-β-葡聚糖均聚、无支链结构有助于提高溶解度，因此，提供了将聚合物加工成所需形状和制剂的替代方案。与此同时，这种相对良好的溶解性使得在温和的条件下进行化学修饰成为可能，导致衍生物化学，结构-性质关系和区域选择性修饰潜力的文献越来越多。结构，性质，生物合成，改性化学，和关键应用的焦点，这篇文献的可得兰审查。
Curdlan is a bacterial polysaccharide that has been of significant recent interest due to its interesting and valuable rheological properties and its inherent bioactivity. The simple (1→3)-β-glucan homopolymeric, unbranched structure of curdlan is conducive to enhanced solubility relative to many other abundant natural polysaccharides, thus, providing alternatives for processing the polymer into desired shapes and formulations. At the same time, this relatively good solubility enables chemical modification under mild conditions, leading to a growing body of literature on derivative chemistry, structure-property relationships, and the potential for regioselective modification. Structure, properties, biosynthesis, modification chemistries, and key applications are the foci for this review of the curdlan literature.