Lymphocytic choriomeningitis virus: Emerging fetal teratogen
Lymphocytic choriomeningitis virus: Emerging fetal teratogen
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DOI：
10.1067/mob.2002.126297
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发表时间：
2002-12-01
影响因子：
9.8
通讯作者：
Beauchamp, CL
中科院分区：
文献类型：
--
作者：
Barton, LL;Mets, MB;Beauchamp, CL
淋巴细胞性脉络丛脑膜炎病毒（LCMV）是一种啮齿类动物传播的沙粒病毒，是一种常未确诊的人类胎儿致畸原。我们描述了一个新生儿出生后，母亲怀孕中期症状LCMV感染脑积水和脉络膜视网膜炎。对以前报告的受影响婴儿进行审查。我们强烈建议产科医生就与受感染的宠物，实验室和家庭小鼠和仓鼠接触对孕妇及其未出生的孩子造成的潜在危害向孕妇提供咨询。
Lymphocytic choriomeningitis virus (LCMV), a rodent-borne, arenavirus, is an often undiagnosed human fetal teratogen. We describe a neonate born with hydrocephalus and chorioretinitis after maternal second-trimester symptomatic LCMV infection. Previously reported affected infants are reviewed. We strongly suggest that obstetricians counsel their pregnant patients regarding the potential hazard that contact with infected pet, laboratory, and household mice and hamsters poses to pregnant women and their unborn children.