The distribution of 10-year risk for coronary heart disease among US adults - Findings from the National Health and Nutrition Examination Survey III
The distribution of 10-year risk for coronary heart disease among US adults - Findings from the National Health and Nutrition Examination Survey III
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DOI：
10.1016/j.jacc.2003.11.061
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发表时间：
2004-05-19
影响因子：
24
通讯作者：
Mokdad, AH
中科院分区：
文献类型：
--
作者：
Ford, ES;Giles, WH;Mokdad, AH
我们试图建立美国成年人中冠心病（CHD）10年风险的分布。CHD风险评估的发展为临床医生提供了一种估计发生CHD的绝对风险的工具。最近，风险评估越来越多地被纳入诊断检测和治疗指南。然而，很少有人知道10年的风险分布冠心病成人在美国的基础上，这些风险评估tools.METHODS我们应用的风险预测算法所使用的国家胆固醇教育计划成人治疗小组III指南的数据，从13,769名参与者（代表157，366，716名美国成年人）年龄在20至79岁之间，在第三次全国健康和营养检查调查中结果在没有自我报告的CHD的参与者中，（心脏病发作和心绞痛）、中风、周围血管疾病和糖尿病的10年中，81.7%（1.4亿成年人）的冠心病风险为20%。10年冠心病风险>20%的参与者比例随着年龄的增长而增加，男性高于女性，但种族或种族差异不大。结论我们的研究结果有助于确定美国成年人10年冠心病风险的分布。(C)2004年，美国心脏病学会基金会。
OBJECTIVES We sought to establish the distribution of the 10-year risk for coronary heart disease (CHD) among U.S. adults.BACKGROUND Risk assessment for CHD was developed to provide clinicians with a tool to estimate the absolute risk of developing CHD. More recently, risk assessment is increasingly being incorporated into guidelines for diagnostic testing and treatment. Yet, little is known about the 10-year risk distribution for CHD among adults in the U.S. based on these risk assessment tools.METHODS We applied the risk prediction algorithm used by the National Cholesterol Education Program Adult Treatment Panel III guidelines to data from 13,769 participants (representing 157,366,716 U.S. adults) age 20 to 79 years in the Third National Health and Nutrition Examination Survey (1988 to 1994).RESULTS Among participants without self-reported CHD (heart attack and angina pectoris), stroke, peripheral vascular disease, and diabetes, 81.7% (140 million adults) had a 10-year risk for CHD of 20%. The proportion of the participants with a 10-year risk for CHD of >20% increased with advancing age and was higher among men than among women but varied little with race or ethnicity.CONCLUSIONS Our results help to define the distribution of 10-year risk for CHD among U.S. adults. (C) 2004 by the American College of Cardiology Foundation.