The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis
The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis
复制标题
超声造影与多普勒超声在肾动脉狭窄分级中的价值
DOI：
10.1155/2020/7145728
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发表时间：
2020-09-08
影响因子：
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通讯作者：
Wu, Ji
中科院分区：
文献类型：
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作者：
Cui, Yanhua;Zhang, Quanbin;Wu, Ji
目的探讨超声造影（CEUS）对肾动脉狭窄分级的准确性。方法选择122条疑似肾动脉狭窄的肾动脉。本研究所有疑似肾动脉狭窄的患者均行DSA、DUS和CEUS检查。DSA被选为金标准。分析超声造影（CEUS）和多普勒超声（DUS）诊断肾动脉狭窄的敏感性、特异性、准确性、阳性预测值（PPV）和阴性预测值（NPV）。比较超声造影与数字减影血管造影（DSA）的一致性。通过受试者工作特征（ROC）曲线下面积评估DUS或CEUS对肾动脉狭窄分级的准确性，并进行组间比较。结果超声造影诊断肾动脉狭窄的敏感性为88.9%，特异性为87.8%，准确性为88.5%，阳性预测值为93.5%，阴性预测值为80.0%。CEUS与DSA对肾动脉狭窄的分级差异无统计学意义（X2 = 0.643, P = 0.424）。超声造影显示，122条肾动脉中有77条狭窄率大于30%。与DSA结果比较，CEUS kappa值为0.749 （P < 0.05）。结论超声造影对肾动脉狭窄分级准确，可作为诊断肾动脉狭窄的首选方法。
Objective This study is aimed at exploring the accuracy of contrast-enhanced ultrasound (CEUS) in grading renal artery stenosis. Methods 122 renal arteries with suspected renal artery stenosis were selected. DSA, DUS, and CEUS were performed for all patients with suspected renal artery stenosis in the research. DSA was selected as the gold standard. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of CEUS or Doppler ultrasound (DUS) in the diagnosis of renal artery stenosis were analyzed. The consistency between CEUS and digital subtraction angiography (DSA) was compared. The accuracy of DUS or CEUS in grading renal artery stenosis was assessed by the area under the receiver operating characteristic (ROC) curves and compared between groups. Results The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CEUS in the diagnosis of renal artery stenosis were 88.9%, 87.8%, 88.5%, 93.5%, and 80.0%, respectively. There was no significant difference in grading renal artery stenosis between CEUS and DSA (X2 = 0.643, P = 0.424). 77 of the 122 renal arteries were diagnosed with the stenosis rate more than 30% by CEUS. Compared with the results of DSA, the kappa value of CEUS was 0.749 (P < 0.05). Conclusion CEUS is accurate in grading renal artery stenosis, and it may represent the method of choice in diagnosing renal artery stenosis.