Imorin: a sexual attractiveness pheromone in female red-bellied newts (Cynops pyrrhogaster).
Imorin: a sexual attractiveness pheromone in female red-bellied newts (Cynops pyrrhogaster).
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Imorin：女性红腹纽氏（Cynops pyrrhogaster）中的性吸引力信息素。
DOI：
10.1038/srep41334
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发表时间：
2017-01-25
影响因子：
4.6
通讯作者：
Kikuyama S
中科院分区：
文献类型：
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作者：
Nakada T;Toyoda F;Matsuda K;Nakakura T;Hasunuma I;Yamamoto K;Onoue S;Yokosuka M;Kikuyama S
雄性红腹蝾螈（Cynops pyrrhogaster）在进行任何求爱行为之前都会接近雌性的泄殖腔，就好像它在用某种释放出来的物质来判断雌性是否接受性行为。因此，我们研究了这种女性性吸引力信息素是否存在。我们发现在性发育的蝾螈输卵管近端上皮的纤毛细胞分泌一种氨基酸序列为Ala-Glu-Phe的三肽，并证实这是性发育的雌性蝾螈所处水中的主要活性物质。这种物质只吸引有性发育的雄性蝾螈，并通过刺激犁鼻上皮细胞起作用。这是在脊椎动物中首次发现的雌性性吸引力肽信息素。
The male red-bellied newt (Cynops pyrrhogaster) approaches the female’s cloaca prior to performing any courtship behaviour, as if he is using some released substance to gauge whether she is sexually receptive. Therefore, we investigated whether such a female sexual attractiveness pheromone exists. We found that a tripeptide with amino acid sequence Ala-Glu-Phe is secreted by the ciliary cells in the epithelium of the proximal portion of the oviduct of sexually developed newts and confirmed that this is the major active substance in water in which sexually developed female newts have been kept. This substance only attracted sexually developed male newts and acted by stimulating the vomeronasal epithelial cells. This is the first female sexual attractiveness peptide pheromone to be identified in a vertebrate.