Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation.
Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation.
复制标题
Mustache:使用尺度空间表示的Hi-C和Micro-C图的染色质环的多尺度检测。
DOI:
10.1186/s13059-020-02167-0
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发表时间:
2020-09-30
期刊:
影响因子:
12.3
通讯作者:
Ay F
中科院分区:
文献类型:
--
作者:
Roayaei Ardakany A;Gezer HT;Lonardi S;Ay F
We present Mustache, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps. Mustache is scalable to kilobase-resolution maps and reports loops that are highly consistent between replicates and between Hi-C and Micro-C datasets. Compared to other loop callers, such as HiCCUPS and SIP, Mustache recovers a higher number of published ChIA-PET and HiChIP loops as well as loops linking promoters to regulatory elements. Overall, Mustache enables an efficient and comprehensive analysis of chromatin loops. Available at: https://github.com/ay-lab/mustache.
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影响因子:
7
作者:
Heidari N;Phanstiel DH;He C;Grubert F;Jahanbani F;Kasowski M;Zhang MQ;Snyder MP
通讯作者:
Snyder MP
影响因子:
5.8
作者:
Cao, Yaqiang;Chen, Zhaoxiong;Han, Jing-Dong J.
通讯作者:
Han, Jing-Dong J.
影响因子:
64.5
作者:
Bonev B;Mendelson Cohen N;Szabo Q;Fritsch L;Papadopoulos GL;Lubling Y;Xu X;Lv X;Hugnot JP;Tanay A;Cavalli G
通讯作者:
Cavalli G
DOI:
10.1111/j.2517-6161.1995.tb02031.x
发表时间:
1995-01-01
影响因子:
5.8
作者:
BENJAMINI, Y;HOCHBERG, Y
通讯作者:
HOCHBERG, Y
影响因子:
7.3
作者:
Chakraborty A;Ay F
通讯作者:
Ay F