An epidemiological survey of overactive bladder symptoms in Japan

An epidemiological survey of overactive bladder symptoms in Japan
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DOI:
10.1111/j.1464-410x.2005.05835.x
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发表时间:
2005-12-01
期刊:
影响因子:
4.5
通讯作者:
Hayashi, K
Hayashi, K
中科院分区:
医学2区
文献类型:
--
作者:
Homma, Y;Yamaguchi, O;Hayashi, K

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目的报道一项下尿路症状(LUTS)的流行病学调查,以确定日本人膀胱过度活动症(OAB)症状(定义为每天尿频8次或以上,每周尿急1次或以上的症状复合体)的患病率。由日本神经源性膀胱协会委员会成员设计的调查问题涵盖四个领域:人口统计特征、LUTS、与健康相关的生活质量(HRQOL)和住院次数。结果分析了4570名受访者(平均年龄61岁)的回答。估计OAB患病率为12.4%(男性14%,女性11%)。有或无紧迫性尿失禁(一次或多次发作/周)的OAB患病率分别为6.4%和6.0%。患病率随着年龄的增长而增加;在40-49岁的受访者中有5%的人患有OAB,在80岁的人中有37%的人患有OAB。在有OAB症状的受访者中,53%的人的HRQOL受到影响,特别是情绪(42%)、睡眠/活力(37%)、身体限制(34%)、角色限制(29%)和社交限制(22%)。在HRQL受影响的人群中,23%(男性36%,女性8%)曾因尿路问题去过医疗机构。结论本次调查结果显示OAB患病率较高,且随年龄增长而增加,但就诊率较低。应提高公众对OAB的认识,以便对这种情况进行最佳管理。
OBJECTIVETo report an epidemiological survey of lower urinary tract symptoms (LUTS) to determine the prevalence of overactive bladder (OAB) symptoms (defined as a symptom complex of daily urinary frequency of eight or more times and urgency once or more per week) in Japan.SUBJECTS AND METHODSA self-administered questionnaire was mailed to 10 096 Japanese men and women aged >= 40 years selected by a two-stage randomized process. Survey questions, developed by members of the Japan Neurogenic Bladder Society Committee, covered four areas: demographic characteristics, LUTS, health-related quality of life (HRQoL), and hospital attendance.RESULTSThe responses from 4570 respondents (mean age 61 years) were analysed. The estimated prevalence of OAB was 12.4% (men 14%, women 11%). Prevalence rates for OAB with and without urgency incontinence (one or more episode/week) were 6.4% and 6.0%, respectively. Prevalence rates increased with age; 5% of respondents aged 40-49 and 37% of those aged >= 80 years had OAB. HRQoL was compromised in 53% of respondents with OAB symptoms, specifically emotions (42%), sleep/vitality (37%), physical limitation (34%), role limitation (29%), and social limitation (22%). Among those whose HRQoL was affected, 23% (men 36%, women 8%) had visited a medical institution because of their urinary problems.CONCLUSIONThe results from this survey indicate that the prevalence of OAB was high and increased with age, but the rate of hospital attendance was low. Public awareness of OAB should be increased so that there can be optimum management of this condition.