Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans
Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans
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DOI：
10.1212/wnl.57.10.1899
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发表时间：
2001-11-27
期刊：
影响因子：
9.9
通讯作者：
Paulus, W
中科院分区：
文献类型：
--
作者：
Nitsche, MA;Paulus, W
作者表明，在人类经颅直流电刺激能够诱导持续的皮质兴奋性升高。如经颅磁刺激所揭示的，运动皮层兴奋性在刺激结束后长达90分钟内比基线增加约150%。以无创、无痛和可逆的方式诱导持久的兴奋性调制的可行性使得该技术成为神经可塑性调制中潜在的有价值的工具。
The authors show that in the human transcranial direct current stimulation is able to induce sustained cortical excitability elevations. As revealed by transcranial magnetic stimulation, motor cortical excitability increased approximately 150% above baseline for up to 90 minutes after the end of stimulation. The feasibility of inducing long-lasting excitability modulations in a noninvasive, painless, and reversible way makes this technique a potentially valuable tool in neuroplasticity modulation.