Incidence of erectile dysfunction in men 40 to 69 years old: Longitudinal results from the Massachusetts male aging study
Incidence of erectile dysfunction in men 40 to 69 years old: Longitudinal results from the Massachusetts male aging study
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DOI：
10.1016/s0022-5347(05)67900-1
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发表时间：
2000-02-01
影响因子：
6.6
通讯作者：
McKinlay, JB
中科院分区：
文献类型：
--
作者：
Johannes, CB;Araujo, AB;McKinlay, JB
目的：我们估计勃起功能障碍的发病率在40至69岁的男性在平均8.8年的随访研究中，并确定风险如何随年龄，社会经济地位和医疗conditions.Materials和方法：数据从随机抽样的人口为基础的纵向研究马萨诸塞州男子进行了分析。在1987年至1989年期间，共有1，709名男性完成了基线访谈，1，156名幸存者在1995年至1997年期间完成了随访。分析样本包括847名基线时没有勃起功能障碍的男性，并有完整的随访信息。勃起功能障碍是通过判别分析的13个问题，从一个自我管理的性功能问卷和一个单一的全球自我rating questions.Results：勃起功能障碍的粗发病率为25.9例每1,000人年（95%置信区间[CI] 22.5至29.9）。年发病率随年龄增长而增加，40 - 49岁、50 - 59岁和60 - 69岁男性的年发病率分别为12.4例/1,000人-年（95% CI 9.0 - 16.9）、29.8例/1,000人-年（24.0 - 37.0）和46.4例/1,000人-年（36.9 - 58.4）。受教育程度较低、患有糖尿病、心脏病和高血压的男性，经年龄调整后的勃起功能障碍风险较高。男性40至69岁的人口预测表明，预计每年在马萨诸塞州和617，715在美国（仅白色男性）的勃起功能障碍的新病例为17，781例。结论：虽然勃起功能障碍的患病率估计和横截面相关性最近已经建立，但缺乏发病率估计。发病率是评估风险、计划治疗和预防策略所必需的。勃起功能障碍的风险每年约为每1,000名男性26例，并随着年龄、教育程度低、糖尿病、心脏病和高血压的增加而增加。
Purpose: We estimated the incidence of erectile dysfunction in men 40 to 69 years old at study entry during an average 8.8-year followup, and determined how risk varied with age, socioeconomic status and medical conditions.Materials and Methods: Data from a randomly sampled population based longitudinal study of Massachusetts men were analyzed. A total of 1,709 men completed the baseline interview during 1987 to 1989 and 1,156 survivors completed followup from 1995 to 1997. The analysis sample consisted of 847 men without erectile dysfunction at baseline and with complete followup information. Erectile dysfunction was assessed by discriminant analysis of 13 questions from a self-administered sexual function questionnaire and a single global self-rating question.Results: The crude incidence rate for erectile dysfunction was 25.9 cases per 1,000 man-years (95% confidence interval [CI] 22.5 to 29.9). The annual incidence rate increased with each decade of age and was 12.4 cases per 1,000 man-years (95% CI 9.0 to 16.9), 29.8 (24.0 to 37.0) and 46.4 (36.9 to 58.4) for men 40 to 49, 50 to 59 and 60 to 69 years old, respectively. The age adjusted risk of erectile dysfunction was higher for men with lower education, diabetes, heart disease and hypertension. Population projections for men 40 to 69 years old suggest; that 17,781 new cases of erectile dysfunction in Massachusetts and 617,715 in the United States (white males only) are expected annually.Conclusions: Although prevalence estimates and cross-sectional correlates of erectile dysfunction have recently been established, incidence estimates were lacking. Incidence is necessary to assess risk, and plan treatment and prevention strategies. The risk of erectile dysfunction was about 26 cases per 1,000 men annually, and increased with age, lower education, diabetes, heart disease and hypertension.