MICROSYNTHESIS OF A NOVEL HERBICIDE,PROPYL 4-[2-[(4,6-DIMETHOXY-2-PYRIMIDINYL)OXY] BENZYLAMINO]BENZOATE
MICROSYNTHESIS OF A NOVEL HERBICIDE,PROPYL 4-[2-[(4,6-DIMETHOXY-2-PYRIMIDINYL)OXY] BENZYLAMINO]BENZOATE
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发表时间：
2006
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通讯作者：
Yang Zheng-min;Ye Qingfu
中科院分区：
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作者：
Yang Zheng-min;Ye Qingfu
ZJ 273，丙基4-[2-[（4，6-二甲氧基-2-嘧啶基）氧基]苄氨基]苯甲酸酯类除草剂是一种新型除草剂，以4，6-二甲氧基-2-嘧啶、丙对苄氨基苯甲酸酯与苯酚反应，经反相高效液相色谱纯化，收率为53%，其化学结构经1H-NMR，MS，UV，所建立的4-[2-[（4，6-二甲氧基-2-嘧啶基）氧基]苄氨基]苯甲酸丙酯的微量合成方法为合成放射性同位素标记的目标化合物奠定了基础。
ZJ273,propyl 4-[2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]benzylamino]benzoate,is a novel herbicide.The microsynthetic method of the compound was developed from 4,6-dimethoxy-2-pyrimidine,propyl(4-benzylamino) benzoate and phenol,and then purified by preparative-HPLC.The yield of end product was 53%.Its chemical structure was characterized by means of()~1H-NMR,MS,UV,and its chemical purity was determined to be exceed 98% by HPLC.The microsynthetic method of propyl 4[2-[(4,6-dimethoxy-2-pyrimidinyl)oxy] benzylamino]benzoate developed sets up a basis to synthesize the radioisotopic labeled target compound.