Cataract in atomic bomb survivors
Cataract in atomic bomb survivors
复制标题
DOI：
10.1080/09553000410001680332
复制
发表时间：
2004-05-01
影响因子：
2.6
通讯作者：
Akahoshi, M
中科院分区：
文献类型：
--
作者：
Minamoto, A;Taniguchi, H;Akahoshi, M
目的：眼科检查进行原子弹（原子弹）幸存者55年后exposure.Materials和方法：原子弹幸存者谁曾在13岁之前，在1945年的轰炸时，或谁曾在以前的研究1978年和1980年之间进行了检查。这些检查于2000年6月至2002年9月期间进行，包括裂隙灯检查、数码摄影以及作为结果变量的透镜三个部分（核、皮质和后囊下）的白内障分级系统。使用最低分级类别作为参考进行比例优势逻辑回归分析，并包括年龄、性别、城市、剂量和各种白内障相关风险因素等解释变量。当一个人的等级不同时，使用最差的等级。结果表明，1 Sv时的比值比（OR）为1.07（95%置信区间[CI] 0.90，1.27），细胞核颜色，1.12皮质性白内障为1.29（95% CI 1.12，1.49），后囊下白内障为1.41（95% CI 1.21，1.64）。排除13人的后囊下白内障已被检测到。结论：在两种类型的白内障在原子弹幸存者中观察到显着的辐射效应。
Purpose : Ophthalmologic examinations were conducted on atomic bomb (A-bomb) survivors 55 years after exposure.Materials and methods : A-bomb survivors who had been exposed before 13 years of age at the time of the bombings in 1945 or who had been examined in a previous study between 1978 and 1980. The examinations, conducted between June 2000 and September 2002, included slit-lamp examination, digital photography and a cataract grading system for three parts of the lens (nucleus, cortex and posterior subcapsule) as an outcome variable. Proportional odds logistic regression analysis was conducted using the lowest grading class as a reference and included explanatory variables such as age, sex, city, dose and various cataract-related risk factors. When the grades in an individual differed, the worst grade was used.Results : Results indicate that odds ratios (ORs) at 1 Sv were 1.07 (95% confidence intervals [CI] 0.90, 1.27) in nuclear colour, 1.12 (95% CI 0.94, 1.30) in nuclear cataract, 1.29 (95% CI 1.12, 1.49) in cortical cataract and 1.41 (95% CI 1.21, 1.64) in posterior subcapsular cataract. The same was true after excluding 13 people whose posterior subcapsular cataracts had been previously detected.Conclusion : Significant radiation effects were observed in two types of cataracts in A-bomb survivors.