Epidemiology of human pulmonary infection with nontuberculous mycobacteria: a review.
Epidemiology of human pulmonary infection with nontuberculous mycobacteria: a review.
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DOI:
10.1016/j.ccm.2014.10.002
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发表时间:
2015-03
影响因子:
5.7
通讯作者:
Marras TK
中科院分区:
文献类型:
--
作者:
Prevots DR;Marras TK
Population-based data have documented a continued increase in NTM prevalence since 2000. Annual prevalence in North American and Australia ranges from 3.2–9.8 per 100,000, and is generally higher than in Europe. Studies of NTM PD from South Korea, Japan, and Taiwan, also suggest increasing prevalence. In Africa and the Middle East, prevalence of NTM ranges from 4% –15% among suspected TB cases and 18%–20% among suspected multi-drug resistant TB (MDR TB) cases. M. avium complex (MAC) is predominant in North America and East Asia, whereas M. kansasii, M. xenopi, and M. malmoense are more common in Europe. Host factors important to the current epidemiology of NTM PD include thoracic skeletal abnormalities, rheumatoid arthritis, and use of immunomodulatory drugs. Clustering of disease within families suggests a heritable genetic predisposition to disease susceptibility. Warm, humid environments with high atmospheric vapor pressure contribute to population risk.
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