Quantitative Study of Rigid-Body and Respiratory Motion of Patients Undergoing Stress and Rest Cardiac SPECT Imaging.
Quantitative Study of Rigid-Body and Respiratory Motion of Patients Undergoing Stress and Rest Cardiac SPECT Imaging.
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DOI：
10.1109/tns.2010.2043852
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发表时间：
2010-06-01
影响因子：
1.8
通讯作者：
King MA
中科院分区：
文献类型：
--
作者：
Mukherjee JM;Johnson KL;McNamara JE;King MA
我们报告了66例患者的110例Tl-201心脏灌注SPECT研究中的患者运动。成像包括发射成像和连续传输成像，在此过程中使用视觉跟踪系统（VTS）进行运动跟踪。我们调查了这些患者呼吸和刚体运动的程度、时间和频率。我们还确定了运动是逐渐发生的还是突然发生的，是持续的，是主要沿着一个或多个轴发生的。然后，我们研究了应激与休息成像组、男性与女性受试者、运动与药物应激组之间呼吸和身体运动（BM）的差异（如果有的话）。我们发现23%的研究在发射成像期间持续运动（bbb4min）在3-6 mm之间，5%的研究持续运动大于6 mm。在呼吸运动方面，13%的患者放射成像时呼吸基线呈下降趋势，下降幅度大于6mm。此外，在9%的研究中，患者的平均位置在发射和透射成像阶段之间移位超过3mm。这两种运动都可能导致衰减图的不对准。在分组研究的假设检验中，确定了压力和休息成像没有显示出身体运动的任何显著差异，但在呼吸运动中显示出与呼吸变化相关的呼吸运动。运动应激研究显示呼吸运动的程度比药物诱导应激研究更大。男性和女性组的身体和呼吸运动也有显著差异。对测量运动的研究中重建的切片进行了视觉评估，以研究运动的影响。包括说明性的例子研究。
We report patient motion in 110 Tl-201 cardiac perfusion SPECT studies in 66 patients. The imaging consisted of emission followed by sequential transmission imaging during which motion tracking with a visual tracking system (VTS) was performed. We investigated the extent, time, and frequency of respiratory and rigid-body motion in these patients. We also determined whether the motion occurred gradually or in sudden jumps, whether it was sustained, and if it occurred along one or more axes predominantly. We then studied the differences in respiratory and body motion (BM), if any, between stress versus rest imaging groups, male versus female subjects, and exercise versus pharmacological stress groups. We found that 23% of the studies had sustained motion (> 4min.) of between 3–6 mm, and 5% had sustained motion larger than 6 mm during emission imaging. In terms of respiratory motion, 13% showed a downward trend of the respiratory baseline of more than 6 mm during emission imaging. Also, in 9% of the studies, the average position of patients was displaced by more than 3 mm between emission and transmission imaging phases. Both of these motions may lead to misalignment of the attenuation map. In hypothesis testing of grouped studies, it was determined that stress and rest imaging did not show any significant differences in body motion but did in respiratory motion associated with a change in respiration following stress. Exercise-stress studies showed a larger extent of respiratory motion than the pharmacologically induced stress studies. Significant differences in body and respiratory motion of male and female groups were also observed. A visual assessment of the reconstructed slices in the studies with measured motion was made to investigate the impact of the motion. Illustrative example studies are included.