Non-invasive estimation by cross sectional echocardiography of myocardial damage in cardiomyopathy.
Non-invasive estimation by cross sectional echocardiography of myocardial damage in cardiomyopathy.
复制标题
通过横断面超声心动图对心肌病心肌损伤进行无创评估。
DOI：
10.1136/hrt.53.2.137
复制
发表时间：
1985
影响因子：
--
通讯作者：
F. Tezuka
中科院分区：
文献类型：
--
作者：
M. Tanaka;S. Nitta;K. Nitta;Y. Sogo;A. Yamamoto;Y. Katahira;N. Sato;H. Ohkawai;F. Tezuka
为了建立一种无创评估心肌病患者心肌内膜变性和纤维化的超声方法，我们对高分辨率横断面超声心动图进行了回顾性和前瞻性研究。心室壁超声心动图与组织学标本比较，在心肌变性和心室壁纤维化部位可见强烈的异常回声。异常回波分为I型、II型、III-1型、III-2型和III-3型。回波强度以I型和III-1型最强，其次是II型和III-2型，最后是III-3型。异常回声强度比正常组织强5 ~ 20分贝，与病变组织的稠度和密度密切相关。这些结果强烈提示，异常心肌回声的来源是变性或纤维化与完整的正常心肌之间的边界，心肌变性和纤维化部位的分布范围和模式在回声模式中得到反映。因此，通过测量回声强度，可以无创地确定心肌变性或纤维化部位的组织特征。
Retrospective and prospective studies of high resolution cross sectional echocardiograms were undertaken in order to establish an ultrasonic method for the non-invasive estimation of degeneration and fibrosis of the endomyocardium in cases of cardiomyopathy. When the echocardiograms of the ventricular wall were compared with the histological specimens intense abnormal echoes were seen at the sites of myocardial degeneration and fibrosis of the ventricular wall. The abnormal echoes classified into five types: types I, II, III-1, III-2, and III-3. Type I and type III-1 echoes were the strongest followed by those of types II and III-2, and then those of type III-3. The intensity of the abnormal echoes was 5-20 decibels stronger than that from intact tissue and was closely related to the consistency and density of the diseased tissue. These findings strongly suggest that the boundary between degeneration or fibrosis and the intact normal myocardium was the source of the abnormal myocardial echoes and that the extent and the pattern of the distribution of the sites of degeneration and fibrosis in the myocardium were reflected in the echo patterns. Thus the tissue characteristics of the sites of degeneration or fibrosis of the myocardium may be determined non-invasively by measuring the echo intensity.