Different types of optic disc shape in patients with advanced open-angle glaucoma
Different types of optic disc shape in patients with advanced open-angle glaucoma
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DOI：
10.1007/s10384-010-0816-y
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发表时间：
2010-07-01
影响因子：
2.4
通讯作者：
Nishida, Kohji
中科院分区：
文献类型：
--
作者：
Nakazawa, Toru;Fuse, Nobuo;Nishida, Kohji
目的：探讨晚期开角型青光眼的特点。进行了一项以医院为基础的回顾性研究。晚期青光眼定义为视力在0.3或以下，或平均偏差在-24 dB或以下。首先，我们筛选晚期青光眼患者并对其青光眼类型进行分类。对于开角型青光眼（OAG）患者，包括原发性开角型青光眼（POAG）和正常眼压型青光眼（NTG），将其椎间盘类型分为局灶性缺血性（FI）、近视型青光眼（MY）、老年性硬化型（SS）和广泛性青光眼（GE）四组。在检查750例青光眼患者的病史后，我们将141例（18.8%）划分为疾病晚期。晚期OAG患者比例为47% （POAG 28%, NTG 19%）。OAG患者视盘表现分类显示，POAG患者以GE型为主（P = 0.0012）， NTG患者以MY型为主（P < 0.0001）。在本研究中伴有严重青光眼损害的OAG患者中，POAG患者的主要椎间盘表型为GE， NTG患者的主要椎间盘表型为MY。
To study the characteristics of patients with advanced open-angle glaucoma.A hospital-based retrospective study was performed. Advanced glaucoma was defined as visual acuity of 0.3 or less, or mean deviation of -24 dB or less. First, we screened patients with advanced glaucoma and classified their glaucoma types. For patients with open-angle glaucoma (OAG), including both primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG), disc types were classified into four groups: focal ischemic (FI), myopic glaucomatous (MY), senile sclerotic (SS), and generalized cup enlargement (GE).After checking the medical history of 750 glaucoma patients, we classified 141 (18.8%) as having the advanced stage of the disease. The proportion of patients with advanced OAG was 47% (28% POAG, 19% NTG). The classification of optic disc appearances in OAG patients showed that in patients with POAG the predominant disc type was GE (P = 0.0012) and in those with NTG it was MY (P < 0.0001).In OAG patients in this study with severe glaucomatous damage, the predominant disc phenotype was GE in patients with POAG and MY in those with NTG.