Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center Experience.
Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center Experience.
复制标题
DOI：
10.5935/abc.20180014
复制
发表时间：
2018-03
影响因子：
2.6
通讯作者：
Leprince P
中科院分区：
文献类型：
--
作者：
Bouabdallaoui N;Demondion P;Maréchaux S;Varnous S;Lebreton G;Mouquet F;Leprince P
Peripartum cardiomyopathy is an idiopathic disorder defined by the occurrence of acute heart failure during late pregnancy or post-partum period in the absence of any other definable cause. Its clinical course is variable and severe cases might require heart transplantation. To investigate long-term outcomes after heart transplantation (HT) for peripartum cardiomyopathy (PPCM). Out of a single-center series of 1938 HT, 14 HT were performed for PPCM. We evaluated clinical characteristics, transplant-related complications, and long-term outcomes, in comparison with 28 sex-matched controls. Primary endpoint was death from any cause; secondary endpoints were transplant-related complications (rejection, infection, cardiac allograft vasculopathy). A value of p < 0.05 was considered of statistical significance. PPCM patients and matched controls were comparable for most variables (all p values > 0.05), except for a higher use of inotropes at the time of HT in PPCM group (p = 0.03). During a median follow-up of 7.7 years, 16 patients died, 3 (21.5%) in PPCM group and 13 (46.5%) in control group. Mortality was significantly lower in PPCM group (p = 0.03). No significant difference was found in terms of transplant-related complications (p > 0.05). Long-term outcomes following HT for PPCM are favorable. Heart transplantation is a valuable option for PPCM patients who did not recover significantly under medical treatment.
登录
查看更多内容
影响因子：
37.8
作者：
Simon, MA;Kormos, RL;McNamara, DM
通讯作者：
McNamara, DM
影响因子：
8.9
作者：
Fett, JD;Christie, LG;Murphy, JG
通讯作者：
Murphy, JG
影响因子：
18.2
作者：
Sliwa, Karen;Hilfiker-Kleiner, Denise;McMurray, John J. V.
通讯作者：
McMurray, John J. V.
影响因子：
18.2
作者：
Mouquet, Frederic;Kara, Meriem Mostefa;de Groote, Pascal
通讯作者：
de Groote, Pascal
DOI：
10.1016/j.ijgo.2007.11.007
发表时间：
2008-05-01
影响因子：
3.8
作者：
Duran, Nilufer;Gunes, Haci;Ozkan, Mehmet
通讯作者：
Ozkan, Mehmet