Representation of Perceptual Color Space in Macaque Posterior Inferior Temporal Cortex (the V4 Complex).
Representation of Perceptual Color Space in Macaque Posterior Inferior Temporal Cortex (the V4 Complex).
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DOI：
10.1523/eneuro.0039-16.2016
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发表时间：
2016-07
期刊：
影响因子：
3.4
通讯作者：
Conway BR
中科院分区：
文献类型：
--
作者：
Bohon KS;Hermann KL;Hansen T;Conway BR
外侧膝状体核被认为是使用两个群体的视锥-对手神经元[L vs M; S vs（L + M）]来代表颜色，它们建立了颜色空间中的基本方向（红色vs青色;淡紫色vs石灰色）。这种表征是如何转化为颜色感知的？先前的工作涉及群体的球细胞在后下颞叶皮层（PIT; V4复合体），但PIT/V4复合体的颜色的神经表征和感知颜色空间的组织之间的对应关系尚不清楚。我们比较了球细胞和interglob细胞的群体的颜色调谐数据，使用不同的颜色调谐窄的细胞，和整个人群的颜色偏好分布的模型获得的预测。球细胞最好由具有非线性（窄）调谐的模拟神经元来解释，并且作为群体，代表被设计为感知均匀（CIELUV）的颜色空间。多维尺度和表征相似性分析表明，在两个球和interglob人口的颜色空间表示与CIELUV空间的组织，但球细胞表现出更强的相关性。色调可以被分类为亮度不变，具有高精度给定的球响应和高于机会的精度给定的interglob响应。亮度可以读出不变的色调在这两个群体中的变化，但interglob细胞往往更喜欢刺激具有亮度对比度，无论色调，而球细胞通常保留色调调谐亮度对比度调制。对于能够在不同亮度水平（橙子/棕色）下区分相同色调的两种颜色的神经元，预测球细胞的组合亮度/色调敏感性。
The lateral geniculate nucleus is thought to represent color using two populations of cone-opponent neurons [L vs M; S vs (L + M)], which establish the cardinal directions in color space (reddish vs cyan; lavender vs lime). How is this representation transformed to bring about color perception? Prior work implicates populations of glob cells in posterior inferior temporal cortex (PIT; the V4 complex), but the correspondence between the neural representation of color in PIT/V4 complex and the organization of perceptual color space is unclear. We compared color-tuning data for populations of glob cells and interglob cells to predictions obtained using models that varied in the color-tuning narrowness of the cells, and the color preference distribution across the populations. Glob cells were best accounted for by simulated neurons that have nonlinear (narrow) tuning and, as a population, represent a color space designed to be perceptually uniform (CIELUV). Multidimensional scaling and representational similarity analyses showed that the color space representations in both glob and interglob populations were correlated with the organization of CIELUV space, but glob cells showed a stronger correlation. Hue could be classified invariant to luminance with high accuracy given glob responses and above-chance accuracy given interglob responses. Luminance could be read out invariant to changes in hue in both populations, but interglob cells tended to prefer stimuli having luminance contrast, regardless of hue, whereas glob cells typically retained hue tuning as luminance contrast was modulated. The combined luminance/hue sensitivity of glob cells is predicted for neurons that can distinguish two colors of the same hue at different luminance levels (orange/brown).