Needle optical coherence elastography for tissue boundary detection
Needle optical coherence elastography for tissue boundary detection
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DOI：
10.1364/ol.37.002310
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发表时间：
2012-06-15
期刊：
影响因子：
3.6
通讯作者：
Sampson, David D.
中科院分区：
文献类型：
--
作者：
Kennedy, Kelsey M.;Kennedy, Brendan F.;Sampson, David D.
我们将，第一次，光学相干弹性成像（OCE）到一个针探头，并证明其能够测量的软组织的微观变形远远超出了报告的深度限制。针OCE利用针尖施加的力作为加载机制，并在插入过程中测量针前方的组织变形。在组织模拟体模和离体猪气管中进行测量。结果证明了基于机械性能的组织分化，并突出了针OCE用于体内组织边界检测的潜力。(C)2012美国光学学会
We incorporate, for the first time, optical coherence elastography (OCE) into a needle probe and demonstrate its ability to measure the microscopic deformation of soft tissues located well beyond the depth limit of reports to date. Needle OCE utilizes the force imparted by the needle tip as the loading mechanism and measures tissue deformation ahead of the needle during insertion. Measurements were performed in tissue-mimicking phantoms and ex vivo porcine trachea. Results demonstrate differentiation of tissues based on mechanical properties and highlight the potential of needle OCE for in vivo tissue boundary detection. (C) 2012 Optical Society of America