Specific innervation of muscle fiber types in a developmentally polyinnervated muscle.
Specific innervation of muscle fiber types in a developmentally polyinnervated muscle.
复制标题
发育中的多神经支配肌肉中肌纤维类型的特定神经支配。
DOI：
10.1016/0012-1606(85)90433-6
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发表时间：
1985
影响因子：
2.7
通讯作者：
VanEssen,DC
中科院分区：
文献类型：
--
作者：
Gordon,H;VanEssen,DC
在新生兔比目鱼肌中，不同的运动单位被发现有很大不同的时间进程。对这些数据的分析表明，尽管出生时存在广泛的多神经支配，但单个运动单位的肌肉纤维类型基本上是相同的。我们认为：(1)新生运动神经元可以有效地分化为特定的类型，因为它们优先支配引起不同收缩时间的肌肉纤维；(2)肌肉纤维开始生理分化为抽动类型，但仍处于多神经支配状态。可能的机制发展的特定模式的神经肌肉神经进行了讨论。
In neonatal rabbit soleus muscle, different motor units were found to contract with widely varying time courses. Analysis of these data suggest that individual motor units are largely homogeneous for muscle fiber type despite the presence of extensive polyinnervation at birth. We suggest that (1) neonatal motor neurons are effectively differentiated into specific types insofar as they preferentially innervate muscle fibers which give rise to different contraction times, and (2) muscle fibers begin their physiological differentiation into twitch types while still polyinnervated. Possible mechanisms underlying the development of a specific pattern of neuromuscular innervation are discussed.