Difficulties in measles elimination: prevalence of measles antibodies before and after mass vaccination campaign in Laos

Difficulties in measles elimination: prevalence of measles antibodies before and after mass vaccination campaign in Laos
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DOI:
10.1016/s0264-410x(02)00480-2
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发表时间:
2003-01-17
期刊:
影响因子:
5.5
通讯作者:
Nakamura, S
Nakamura, S
中科院分区:
医学3区
文献类型:
--
作者:
Kuroiwa, C;Xayyavong, P;Nakamura, S

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为响应2000年区域消灭小儿麻痹症宣言,西太平洋区域一直在加强消灭麻疹的努力。尽管如此,我们对在老挝消灭麻疹的可行性提出了质疑,因为那里的麻疹仍然是地方病。本研究通过比较2000年麻疹疫苗接种前后两个试点地区9月~ 4岁儿童麻疹抗体的流行情况,探讨大规模麻疹疫苗接种运动的效果。本研究探讨了大规模疫苗接种运动的制约因素。报告还建议,应加大努力重建老挝现有的常规免疫服务,因为该服务已被积极的根除计划削弱。(C)2002爱思唯尔科技有限公司。保留所有权利。
Responding to the declaration of regional polio eradication in 2000, Western Pacific Region (WPR) has been strengthening the efforts for measles elimination. Nevertheless, we questioned the feasibility of the measles elimination in Laos, where measles was still endemic. This study was undertaken with the aim to examine the impact of mass measles vaccination campaign, by comparing the prevalence of measles antibodies between before and after the campaign in 2000, among the children aged 9 months to 4 years in the two pilot sites. The constraints of mass vaccination campaign have been explored in this study. It was also suggested that more efforts should be put on reconstruction of the existing routine immunization service in Laos, which had been weakened by aggressive eradication programme. (C) 2002 Elsevier Science Ltd. All rights reserved.