ras gene mutations in oral cancer in eastern India
ras gene mutations in oral cancer in eastern India
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DOI：
10.1016/s1368-8375(99)00058-5
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发表时间：
2000-01-01
期刊：
影响因子：
4.8
通讯作者：
DasGupta, UB
中科院分区：
文献类型：
--
作者：
Das, N;Majumder, J;DasGupta, UB
应用选择性寡核苷酸杂交和聚合酶链式反应扩增产物的限制性片段长度多态性分析，对50例东印度人口腔肿瘤标本进行了H-、K-和N-ras基因突变的研究。H-ras和K-ras基因突变频率分别为28%和33%，未发现N-ras基因突变。(C)2000由爱思唯尔科学有限公司出版。版权所有。
Oral tumor specimens (n = 50) from eastern Indian population were studied for the presence of mutations in the H-, K- and N-ras genes using selective oligodeoxynucleotide hybridization and restriction fragment length polymorphism analysis of polymerase chain reaction-amplified products. Mutations in H- and K-ras genes were observed at a frequency of 28 and 33%, respectively, whereas no N-ras mutation was noticed. (C) 2000 Published by Elsevier Science Ltd. All rights reserved.