Direction-dependent conduction in lone atrial fibrillation
Direction-dependent conduction in lone atrial fibrillation
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DOI：
10.1016/j.hrthm.2010.05.037
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发表时间：
2010-09-01
期刊：
影响因子：
5.5
通讯作者：
Sanders, Prashanthan
中科院分区：
文献类型：
--
作者：
Wong, Christopher X.;Stiles, Martin K.;Sanders, Prashanthan
背景：单纯性心房颤动（AF）患者有异常的心房底物。目的探讨方向依赖性传导在单纯性房颤中的作用。方法对24例阵发性单纯性房颤患者和24例左侧辅助通路的对照患者进行研究。多极导管放置于右心房外侧、终嵴、冠状窦（CS）和左心房顶，以测定方向依赖性传导特性。在窦性心律和远端CS起搏时创建双房电解剖图，以表征传导速度、电图复杂性和电压的方向依赖性差异。结果不同波前方向对传导速度(P
BACKGROUND Patients with lone atrial fibrillation (AF) have an abnormal atrial substrate.OBJECTIVE The purpose of this study was to determine the role of direction-dependent conduction in patients with lone AF.METHODS Twenty-four patients with paroxysmal lone AF and 24 reference patients with left-sided accessory pathways were studied. Multipolar catheters placed at the lateral right atrium, crista terminalis, coronary sinus (CS), and left atrial roof were used to determine direction-dependent conduction characteristics. Biatrial electroanatomic maps were created during sinus rhythm and with distal CS pacing to characterize direction-dependent differences in conduction velocities, electrogram complexity, and voltage.RESULTS Differing wavefront directions caused changes in conduction velocity (P