TMS 2022 151st Annual Meeting & Exhibition Supplemental Proceedings
TMS 2022 151st Annual Meeting & Exhibition Supplemental Proceedings
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TMS 2022 第 151 届年会
DOI：
10.1007/978-3-030-92381-5_73
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Yildizbakan L
中科院分区：
文献类型：
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作者：
Yildizbakan L
我们已经开发了双层骨传导和抗菌支架，它模仿骨的自然结构。合成皮质（1型）生物材料由嵌入10%铁掺杂透钙磷石矿物的多孔钛制成。骨小梁（2型）生物材料由冻干多孔壳聚糖与10%掺铁透钙磷石和氧化铈溶液包埋制成。1型和2型生物材料在保持在-100 ℃和40 mTorr压力的室中的冷冻干燥过程中结合;这种方法有助于骨小梁和皮质生物材料的整合，从而形成双层支架。使用拉曼、傅里叶变换红外（FTIR）光谱、能量色散X射线（EDX）光谱和扫描电子显微镜（SEM）表征双层支架的物理化学和结构。
We have developed two-layered osteoconductive and antibacterial scaffolds, which mimic the natural structure of bone. The synthetic cortical (Type-1) biomaterials were fabricated from porous titanium embedded with 10% iron-doped brushite minerals. The trabecular (Type-2) biomaterials were fabricated from freeze-dried porous chitosan embedded with 10% iron-doped brushite and cerium oxide solution. The Type-1 and Type-2 biomaterials were conjoined during a freeze-drying process in a chamber maintained at −100 ℃ and 40 mTorr pressure; this approach aided the integration of the trabecular and cortical biomaterials, thus forming dual-layered scaffold. The two-layered scaffolds were characterised using Raman, and Fourier Transform Infrared (FTIR) Spectroscopy, Energy-Dispersive X-ray (EDX) Spectroscopy and Scanning Electron Microscopy (SEM) for their physicochemical and structural.