Cardiac Troponin I Elevation in Patients with Aneurysmal Subarachnoid Hemorrhage

Cardiac Troponin I Elevation in Patients with Aneurysmal Subarachnoid Hemorrhage
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DOI:
10.3340/jkns.2009.46.2.99
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发表时间:
2009-08-01
影响因子:
1.6
通讯作者:
Kim, Seong-Ho
Kim, Seong-Ho
中科院分区:
医学4区
文献类型:
--
作者:
Jeon, Ik-Chan;Chang, Chul-Hoon;Kim, Seong-Ho

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目的:蛛网膜下腔出血(SAH)后心功能不全与血清心肌肌钙蛋白I(cTnI)水平升高有关。cTnI升高预示心肺和神经系统并发症,预后不佳。方法:我们回顾性分析了114例(男:30,女:84)患者的医疗和放射学记录,这些患者在2006年1月至2007年6月期间发生了蛛网膜下腔出血,既往无心脏问题。我们评估了他们的心电图和cTnI水平,这是在入院时测量的。cTnI水平高于0.5 μ g/L被定义为SAH后心脏损伤的指标。采用SPSS12.0软件包,对各临床因素与cTnI升高的相关性进行卡方检验、t检验和Logistic回归分析。结果被认为在p
Objective : Cardiac dysfunction after aneurysmal subarachnoid hemorrhage (SAH) is associated with elevation of serum cardiac troponin I (cTnI) levels. Elevation of cTnI predicts cardiopulmonary and neurological complications, and poor outcome.Methods : We retrospectively reviewed the medical and radiologic records of 114 (male : 30, female : 84) patients who developed aneurysmal SAH between January 2006 and June 2007 and had no history of previous cardiac problems. We evaluated their electrocardiography and cTnI level, which had been measured at admission. A cTnI level above 0.5 mu g/L was defined as an indicator of cardiac injury following SAH. We examined various clinical factors for their association with cTnI elevation and analyzed data using chi-square test, t-test and logistic regression test with SPSS version 12.0. The results were considered significant at p