Pattern formation in the lateral line of zebrafish

Pattern formation in the lateral line of zebrafish
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DOI:
10.1016/s0925-4773(01)00382-3
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发表时间:
2001-07-01
影响因子:
2.6
通讯作者:
Ghysen, A
Ghysen, A
中科院分区:
生物学4区
文献类型:
--
作者:
Gompel, N;Cubedo, N;Ghysen, A

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鱼和两栖动物的侧线是一个感官系统,它包括一些单独的感觉器官,即神经肥大,在身体表面以一定的模式排列。该系统的一个显眼部分是沿侧翼延伸的一系列器官(这就是该系统的名字)。在斑马鱼胚胎发育结束时,这条线由7-8根神经肥大组成,它们规则地排列在耳朵和尾巴的顶端之间。神经肥大是由起源于耳区的迁徙原基沉积的。在这里,我们跟踪这一模式的发展,并表明迁移原基内的异质性预示着神经肥大的形成。(C)2001爱思唯尔爱尔兰科学有限公司。保留所有权利。
The lateral line of fish and amphibians is a sensory system that comprises a number of individual sense organs, the neuromasts, arranged in a defined pattern on the surface of the body. A conspicuous part of the system is a line of organs that extends along each flank (and which gave the system its name). At the end of zebrafish embryogenesis, this line comprises 7-8 neuromasts regularly spaced between the ear and the tip of the tail. The neuromasts are deposited by a migrating primordium that originates from the otic region. Here, we follow the development of this pattern and show that heterogeneities within the migrating primordium prefigure neuromast formation. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.