Initial Evaluation of LabPET/SPECT Dual Modality Animal Imaging System
Initial Evaluation of LabPET/SPECT Dual Modality Animal Imaging System
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DOI：
10.1109/tns.2012.2233216
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发表时间：
2013-01
影响因子：
1.8
通讯作者：
R. Yao;Xiao Deng;J. Beaudoin;Tianyu Ma;J. Cadorette;Z. Cao;R. Lecomte
中科院分区：
文献类型：
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作者：
R. Yao;Xiao Deng;J. Beaudoin;Tianyu Ma;J. Cadorette;Z. Cao;R. Lecomte
我们在LabPET动物扫描仪上开发了SPECT成像功能，以提供集成的PET/SPECT双模态成像系统。通过以下方式启用附加SPECT子系统：1）在PET探测器环中机械集成多针孔准直器，2）配置探测器以采集120-160 keV范围内的单个事件。我们报告的设计参数，数据采集协议和初步性能评估，这种具有成本效益的SPECT成像解决方案。幻影和动物的图像，证明了在临床前研究的各种成像任务的系统的相关性。
We developed SPECT imaging capability on a LabPET animal scanner to provide an integrated PET/SPECT dual-modality imaging system. The add-on SPECT sub-system was enabled by 1) mechanically integrating a multiple-pinhole collimator in the PET detector ring, and 2) configuring the detectors to acquire singles events in the 120-160 keV range. We report on the design parameters, data acquisition protocols and initial performance assessment of this cost-effective SPECT imaging solution. Phantom and animal images demonstrating the relevance of the system for various imaging tasks in preclinical research are presented.