A CONTROLLED-STUDY OF BRAIN MAGNETIC-RESONANCE-IMAGING IN PATIENTS WITH THE CHRONIC FATIGUE SYNDROME
A CONTROLLED-STUDY OF BRAIN MAGNETIC-RESONANCE-IMAGING IN PATIENTS WITH THE CHRONIC FATIGUE SYNDROME
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DOI：
10.1016/0022-510x(93)90276-5
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发表时间：
1993-12-15
影响因子：
4.4
通讯作者：
LEE, HJ
中科院分区：
文献类型：
--
作者：
NATELSON, BH;COHEN, JM;LEE, HJ
两名神经放射学家比较了52名符合CDC慢性疲劳综合征（CFS）标准的患者的脑部MR扫描与52名年龄和性别匹配的对照组，这些对照组因头部创伤或头痛病史而接受了成像。CFS患者的异常扫描明显多于对照组--27%vs2%。9例CFS患者和1例对照组患者的病灶均为白色T2信号增加，5例CFS患者的病灶均为脑室或脑沟扩大。对皮质下信号高信号患者的随访显示，3例患者的症状提示其他已知的CFS医学原因。这些数据表明，一些CFS患者有一些器质性问题，表现在神经影像学上。但是，发现MR异常应该警告医生，患者的症状可能是继发于其他一些医学疾病，而不仅仅是原发性CFS。
Two neuroradiologists compared the brain MR scans of 52 patients with the CDC criteria for the chronic fatigue syndrome (CFS) with those of 52 age and sex matched controls who had undergone imaging because of histories of head trauma or headache. CFS patients had significantly more abnormal scans than controls -27% vs 2%. Abnormalities seen were foci of increased white matter T2 signal in 9 CFS patients and one control and ventricular or sulcal enlargement in 5 CFS patients. Follow up of patients with subcortical signal hyperintensities revealed 3 who had symptoms suggestive of other known medical causes of what appeared to be CFS. The data indicate that some CFS patients have some organic problem manifesting itself on neuroimaging. But, finding MR abnormalities should warn the physician that the patient's symptoms may be secondary to some other medical illness and not simply primary CFS.