Minimally invasive liver resection for hepatocellular carcinoma of patients with liver damage B: A propensity score-based analysis
Minimally invasive liver resection for hepatocellular carcinoma of patients with liver damage B: A propensity score-based analysis
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DOI：
10.1111/hepr.13057
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发表时间：
2018-06-01
影响因子：
4.2
通讯作者：
Mori, Masaki
中科院分区：
文献类型：
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作者：
Noda, Takehiro;Eguchi, Hidetoshi;Mori, Masaki
目的微创肝切除术（MILR）是治疗肝脏恶性肿瘤安全可行的方法。然而，很少有研究调查肝功能受损患者的MILR手术结果。肝损伤用于考虑肝切除术。本研究的目的是阐明MILR的疗效与肝功能损害患者通过使用倾向评分matching.MethodsNine 9例肝损害B行肝切除术进行了分析。将患者分为两组，MILR组（n=24）和开放性肝切除术（OLR）组（n=75）。匹配的倾向评分后，我们比较了临床病理特征和手术outcomes.ResultsAfter匹配，36例（每组18例）被选中，患者的特点和肿瘤的特点是没有显着差异两组之间。MILR组的失血量（P=0.0163）和并发症发生率（P=0.0162）显著降低。在8名患者中观察到并发症，包括MILR组的1名患者和OLR组的7名患者。MILR组术后住院时间明显缩短（P=0.0118）。它减少了手术并发症，从而缩短了住院时间。
AimMinimally invasive liver resection (MILR) is considered a safe and feasible treatment for malignant liver tumors. However, few studies have investigated the surgical outcomes of MILR in patients with impaired liver function. Liver damage is used for consideration of hepatectomy. The aim of this study is to clarify the efficacy of MILR for patients with impaired liver function by using propensity score matching.MethodsNinety-nine patients with liver damage B underwent hepatic resection were analyzed. The patients were divided into two groups, the MILR group (n=24) and the open liver resection (OLR) group (n=75). After matching of a propensity score, we compared clinicopathological features and surgical outcomes.ResultsAfter matching, 36 patients (18 patients from each group) were selected and the patients' characteristics and tumor characteristics were not significantly different between the two groups. Blood loss (P=0.0163) and complication rate (P=0.0162) were significantly decreased in the MILR group. Complications were observed in eight patients, comprising one patient in the MILR group and seven patients in the OLR group. The postoperative hospital stay was significantly shortened in the MILR group (P=0.0118).ConclusionMinimally invasive liver resection might be effective for patients with impaired liver function. It reduces surgical complications and consequently shortens hospitalization time.