Renal volumetry with magnetic resonance imaging.
Renal volumetry with magnetic resonance imaging.
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DOI：
10.1177/2058460117731120
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发表时间：
2017-09
影响因子：
1.1
通讯作者：
Brismar TB
中科院分区：
文献类型：
--
作者：
Christensen RH;Lundgren T;Stenvinkel P;Brismar TB
体内肾容量不存在金标准。设计和评估磁共振成像 (MRI) 数据集的分割方法。使用 MRI 脉冲序列和测量方法的五种组合来测量 5 名 54-72 岁男性在自体肾干细胞移植前以及移植后 3、6 和 12 个月扫描的肾脏体积。干细胞移植后肾体积没有变化。结果差异很大：再现性（变异系数）为 4.0-6.0%，每个肾脏的测量时间为 1-13 分钟。在没有脂肪饱和序列的情况下，对体积插值屏气检查 (VIBE) 图像进行手动分割可提供最佳的再现性，但非常耗时。使用半傅立叶采集单次涡轮自旋回波 (HASTE) 的椭球公式提供了最快的测量，但导致再现性较低。基于使用异相 TE 获取的无脂肪饱和的脉冲序列 VIBE 图像的肾容量可以进一步研究，可能与快速椭球公式相结合。
No gold standard exists for renal volumetry in vivo. To devise and evaluate segmentation methods on magnetic resonance imaging (MRI) datasets. Five combinations of MRI pulse sequences and measuring methods were used to measure the renal volumes of five men aged 54–72 years scanned before autologous renal stem cell transplantation and three, six, and 12 months post transplantation. Renal volume did not change after stem cell transplantation. The results varied considerably: the reproducibility (coefficient of variation) was 4.0–6.0% and measurements took 1–13 min per kidney. Manual segmentation of images from the volumetric interpolated breath-hold examination (VIBE) without fat saturation sequence provided best reproducibility but was time-consuming. Use of the ellipsoid formula from half Fourier acquisition single shot turbo spin echo (HASTE) provided the fastest measurement, but resulted in lower reproducibility. Renal volumetry based on images from the pulse sequence VIBE without fat saturation acquired using an out-of-phase TE may be investigated further, possibly in combination with the quick ellipsoid formula.