Mouse Phenome Database (MPD).
Mouse Phenome Database (MPD).
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DOI：
10.1093/nar/gkl1049
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发表时间：
2007-01
影响因子：
14.9
通讯作者：
Bult CJ
中科院分区：
文献类型：
--
作者：
Bogue MA;Grubb SC;Maddatu TP;Bult CJ
小鼠表型数据库（MPD;）是一个关于常用和遗传多样性近交系小鼠的表型和基因型数据库。菌株特征数据由科学界成员提供。对集中式菌株数据的电子访问使生物医学研究人员能够为许多基于系统的研究应用选择合适的菌株，包括生理学研究、药物和毒理学测试以及疾病过程建模。MPD提供了一个社区数据存储库和一个数据分析和计算机假设检验的平台。实验室小鼠是了解人类生物学和病理学的首要遗传模型; MPD促进了使用小鼠识别和确定参与正常和疾病途径的基因功能的研究。
The Mouse Phenome Database (MPD; ) is a repository of phenotypic and genotypic data on commonly used and genetically diverse inbred strains of mice. Strain characteristics data are contributed by members of the scientific community. Electronic access to centralized strain data enables biomedical researchers to choose appropriate strains for many systems-based research applications, including physiological studies, drug and toxicology testing and modeling disease processes. MPD provides a community data repository and a platform for data analysis and in silico hypothesis testing. The laboratory mouse is a premier genetic model for understanding human biology and pathology; MPD facilitates research that uses the mouse to identify and determine the function of genes participating in normal and disease pathways.