Synthesis of Multiblock Copolymers by Coupling Reaction Based on Self-Assembly and Click Chemistry
Synthesis of Multiblock Copolymers by Coupling Reaction Based on Self-Assembly and Click Chemistry
复制标题
DOI：
10.1021/ma802291w
复制
发表时间：
2008-12
期刊：
影响因子：
5.5
通讯作者：
Wanjuan Wang;Ting Li;T. Yu;Fangming Zhu
中科院分区：
文献类型：
--
作者：
Wanjuan Wang;Ting Li;T. Yu;Fangming Zhu
分别制备了双端叠氮基封端和双端炔基封端的聚环氧乙烷-b-聚环氧丙烷-b-聚环氧乙烷三嵌段共聚物（N3-PEO-b-PPO-b-PEO-N3和HC（C-PEO-b-PPO-b-PEO-CH）），并将其作为自组装和点击化学相结合的偶联反应的前体合成了多嵌段共聚物。等摩尔的所得三嵌段共聚物在水（PEO的选择性溶剂）中的自组装导致核-壳结构，其中不溶性和塌陷的PPO嵌段作为核，可溶性和溶胀的PEO嵌段作为壳。自组装集中并暴露了周边的叠氮基和炔基端基。进行了自组装双末端官能化三嵌段共聚物之间的多重点击偶联反应，导致高效形成−（−PEO-b-PPO-b-PEO−）n−多嵌段共聚物链。比较了在N，N-二甲基甲酰胺（DM）溶剂中的点击偶联反应。
Diends-azido-terminated and diends-alkynyl-terminated poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) triblock copolymers (N3-PEO-b-PPO-b-PEO-N3 and HC≡C-PEO-b-PPO-b-PEO-C≡CH) were respectively prepared and used together as the precursors for multiblock copolymer synthesis through coupling reaction by combination of self-assembly and click chemistry. The self-assembly of equimolar resultant triblock copolymers in water, a selective solvent for PEO, results in a core−shell structure with the insoluble and collapsed PPO blocks as the core and the soluble and swollen PEO blocks as the shell. The self-assembly concentrates and exposes the azido and alkynyl end groups on the periphery. The multiple click coupling reactions between the self-assembled diends-functionalized triblock copolymers were performed, leading to the highly efficient formation of −(−PEO-b-PPO-b-PEO−)n− multiblock copolymer chains. In comparison, the click coupling reaction was also presented in N,N-dimethylformamide (DM...