Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey: clinical action thresholds
Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey: clinical action thresholds
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DOI：
10.1093/ajcn/76.4.743
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发表时间：
2002-10-01
影响因子：
7.1
通讯作者：
Heymsfield, SB
中科院分区：
文献类型：
--
作者：
Zhu, SK;Wang, ZM;Heymsfield, SB
背景：腰围（WC）与肥胖相关的风险密切相关。然而，目前提出的腰围风险阈值不是基于与肥胖相关的危险因素，而是基于体重指数（BMI，单位为kg/m(2)）。目的：目的是确定美国白人代表性样本中WC与肥胖相关危险因素的关系，并得出WC和BMI的可比风险阈值。设计：第三次全国健康与营养检查调查9019名白人参与者的数据根据存在大于等于4种肥胖相关危险因素中的1种分为两组：低高密度脂蛋白胆固醇、高低密度脂蛋白胆固醇、高血压和高血糖。以研究人群中第25百分位为参考，从WC和BMI的logistic回归模型中导出比值比（OR）方程，计算用于识别WC和BMI危险因素的受试者工作特征曲线。结果：bmi为25和30时，男性的or分别为1.19 （95% CI: 1.06, 1.35）和2.37 (95% CI: 1.33, 4.22)，女性的or分别为1.56 （95% CI: 1.29, 1.91）和3.16 （95% CI: 1.94, 5.28）。男性WC对应的or值为90和100 cm，女性为83和93 cm，男性WC的最小值为96 cm， BMI的最小值为26，女性WC的最小值为86 cm， BMI的最小值为25。结论：与BMI相比，腰围与心血管疾病危险因素的关系更为密切。
Background: Waist circumference (WC) is strongly linked to obesity-associated risks. However, currently proposed WC risk thresholds are not based on associations with obesity-related risk factors but rather with body mass index (BMI; in kg/m(2)).Objective: The objective was to determine the relations of WC to obesity-associated risk factors in a representative sample of US whites and to derive comparable risk thresholds for WC and BMI.Design: Data on 9019 white participants of the third National Health and Nutrition Examination Survey were divided into 2 groups according to the presence of greater than or equal to 1 of 4 obesity-associated risk factors: low HDL cholesterol, high LDL cholesterol, high blood pressure, and high glucose. Odds ratio (OR) equations were derived from logistic regression models for WC and BMI with the use of the 25th percentile in the study population as the reference, Receiver operating characteristic curves for identifying risk factors were computed for WC and BMI.Results: At BMIs of 25 and 30, ORs were 1.19 (95% CI: 1.06, 1.35) and 2.37 (95% CI: 1.33, 4.22) for men and 1.56 (95% CI: 1.29, 1.91) and 3.16 (95% CI: 1.94, 5.28) for women, respectively. The corresponding ORs for WC were at 90 and 100 cm for men and at 83 and 93 cm for women, Minima on the receiver operating characteristic curves for men were at 96 cm for WC and at 26 for BMI and for women were at 86 cm for WC and 25 for BMI.Conclusion: WC is more closely linked to cardiovascular disease risk factors than is BMI.