Resonance assignments of the metal sensor CzrA in the apo-, Zn2- and DNA-bound (42 kDa) states

Resonance assignments of the metal sensor CzrA in the apo-, Zn2- and DNA-bound (42 kDa) states
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DOI:
10.1007/s12104-007-9027-y
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发表时间:
2007-07-01
影响因子:
0.9
通讯作者:
Giedroc, David P.
Giedroc, David P.
中科院分区:
生物学4区
文献类型:
--
作者:
Arunkumar, Alphonse I.;Pennella, Mario A.;Giedroc, David P.

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锌/钴与同源二聚体的结合抑制金黄色葡萄球菌抗钴锌操纵子的转录。给出了apo-,Zn(2)和42 kDa apo-chrA-DNA络合物的基本完整的主链和立体特异性甲基的共振归属。
Zn/Co binding to homodimeric CzrA de-represses transcription of the czr (cobalt zinc resistance) operon in Staphylococcus aureus. Essentially complete backbone and stereospecific methyl group resonance assignments for apo-, Zn(2) and a 42 kDa apo- CzrA-DNA complex are presented.