(+) RNA virus replication compartments: a safe home for (most) viral replication.
(+) RNA virus replication compartments: a safe home for (most) viral replication.
复制标题
DOI：
10.1016/j.mib.2016.05.003
复制
发表时间：
2016-08
影响因子：
5.4
通讯作者：
Randall G
中科院分区：
文献类型：
--
作者：
Shulla A;Randall G
（+）RNA病毒复制区室形成两种结构类别。这两类复制区室都使用细胞膜曲率蛋白。这两类复制隔室操纵从头脂质合成。一些双膜囊泡利用细胞脂质激酶和转运蛋白。有限的瞬时复制可能发生在复制区室形成之前。本文综述了（+）RNA病毒建立复制生态位机制的最新进展。
(+) RNA virus replication compartments form two structural classes. Both classes of replication compartments use cellular membrane curvature proteins. Both classes of replication compartments manipulate de novo lipid synthesis. Some double membrane vesicles use cellular lipid kinases and transfer proteins. Limited transient replication may occur before replication compartment formation. This review describes recent advances in our understanding of the mechanisms by which (+) RNA viruses establish their replication niche.