SUBSTANCE-P - CORRELATION OF CSF AND PLASMA-LEVELS
SUBSTANCE-P - CORRELATION OF CSF AND PLASMA-LEVELS
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DOI：
10.1111/j.1526-4610.1994.hed3405261.x
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发表时间：
1994-05-01
期刊：
影响因子：
5
通讯作者：
GALLAGHER, C
中科院分区：
文献类型：
--
作者：
CLARK, JW;SENANAYAKE, PD;GALLAGHER, C
Objective: To determine the correlation between cerebrospinal fluid and plasma concentrations of substance P.Patients: 37 patients undergoing lumbar puncture for various diagnostic purposes.Measurements: Samples of cerebrospinal fluid and blood were obtained at the same visit. Substance P was measured by radioimmunoassay technique. At least 4 separate measurements were conducted on each sample to insure accuracy.Results: The mean plasma SP level was 1.195 (+/- 1.1). The mean cerebrospinal fluid substance P level was 1.075 (+/- .07). There was a statistically significant positive correlation between substance P level in the plasma and cerebrospinal fluid. The Pearson correlation coefficient was 0.656 (P
