Detection of impaired gas exchange using the 1-minute sit-to-stand test in patients with interstitial lung disease
Detection of impaired gas exchange using the 1-minute sit-to-stand test in patients with interstitial lung disease
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DOI：
10.1016/j.resinv.2022.12.009
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发表时间：
2023-01-30
影响因子：
3.1
通讯作者：
Matsunaga, Kazuto
中科院分区：
文献类型：
--
作者：
Oishi, Keiji;Asami-Noyama, Maki;Matsunaga, Kazuto
工作背景：尽管肺功能检查（PFT）对间质性肺病（ILD）患者很重要，但在初级医疗机构中不易进行。本研究旨在检查静息时脉搏血氧饱和度（SpO 2）与1分钟坐立试验期间最低SpO 2之间差异的有用性方法：回顾性分析116例ILD患者行1STST和PFT的临床资料。Δ SpO 2 -1STST与一氧化碳弥散量（DLco）呈强相关（r = 0.70）。Δ SpO 2 -1STST可有效预测气体交换受损（临界值，-4%，AUC，0.86;敏感性，74%;特异性，87%）。结论：Δ SpO 2 -1STST可作为预测PFT异常的合理工具。(c)2023日本呼吸学会Elsevier B. V.出版，保留所有权利。
Background: Although pulmonary function tests (PFTs) are important in patients with interstitial lung disease (ILD), they cannot be easily performed in a primary healthcare setting. This study aimed to examine the usefulness of the difference between pulse ox-ygen saturation (SpO2) at rest and the lowest SpO2 during the 1-min sit-to-stand test (delta SpO2-1STST) for predicting pulmonary function impairment.Methods: We retrospectively reviewed 116 patients with ILD who underwent 1STST and PFTs.Results: The delta SpO2-1STST and diffusing capacity for carbon monoxide (DLco) strongly correlated (r = 0.70). The delta SpO2-1STST was effective in predicting impaired gas ex-change (cut-off value,-4%; AUC, 0.86; sensitivity, 74%; specificity, 87%).Conclusions: The Delta SpO2-1STST may be a reasonable tool for predicting abnormalities in PFTs.(c) 2023 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.