SUB-CELLULAR LOCALIZATION AND SOME PROPERTIES OF MONOACYLGLYCEROL LIPASE IN RAT ADIPOCYTES
SUB-CELLULAR LOCALIZATION AND SOME PROPERTIES OF MONOACYLGLYCEROL LIPASE IN RAT ADIPOCYTES
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DOI：
10.1093/oxfordjournals.jbchem.a133607
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发表时间：
1981-01-01
影响因子：
2.7
通讯作者：
NOMA, A
中科院分区：
文献类型：
--
作者：
SAKURADA, T;NOMA, A
本文研究了单酰甘油脂肪酶在大鼠脂肪细胞中的亚细胞定位。酶活性主要分布在细胞膜和胞浆中。两个亚细胞部位的单酰甘油脂肪酶活性的性质几乎相同，只是热稳定性略有不同。脂肪组织中可能存在两种单酰甘油脂肪酶，它们作用于两种三酰甘油脂肪酶、脂蛋白脂肪酶和激素敏感脂肪酶而形成的单甘油水解酶。
The subcellular localization of monoacylglycerol lipase in rat adipocytes was studied. The enzyme activities were mainly found in the plasma membrane and in the cytosol fraction. The properties of the monoacylglycerol lipase activities, from both subcellular sites, were almost identical, except for slight differences in thermostability. There may be 2 kinds of monoacylglycerol lipases in adipose tissue for the hydrolysis of the monoacylglycerols formed by the action of 2 kinds of triacylglycerol lipases, lipoprotein lipase and hormone-sensitive lipase.