Stroke mortality in urban and rural Tanzania

Stroke mortality in urban and rural Tanzania
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DOI:
10.1016/s0140-6736(00)02240-6
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发表时间:
2000-05-13
期刊:
影响因子:
168.9
通讯作者:
Alberti, KGMM
Alberti, KGMM
中科院分区:
医学1区
文献类型:
--
作者:
Walker, RW;McLarty, DG;Alberti, KGMM

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撒哈拉以南非洲地区的大多数中风死亡率数据都是基于医院的。我们的目的是建立脑血管疾病对坦桑尼亚一个城市和两个农村地区15岁或以上成人全因死亡率和脑血管疾病死亡率的贡献。(125932名15岁以下及181888名15岁或以上),并对一九九二年六月一日至一九九五年五月三十一日期间在这些人口中发生的所有死亡个案进行前瞻性监察。口头尸检是与死者的亲属或照顾者一起完成的。在可能的情况下。结果:在3年的观察期内,11 975例死亡记录在三个监测区,其中7629例(64%)是15岁或以上的成年人(4088例[54%]男性和3541例[46%]女性)。在成人中,421例(5.5%)死亡归因于脑血管疾病,其中225例(53%)为男性,196例(47%)为女性。在三个项目地区(分别为城市、相当富裕的农村和贫困农村),15-64岁年龄组的年年龄调整率为每100 000人65(95% CI 39-90)、44(31-56)和35(22-48)。女性为88(48-128)、33(22-43)和27(16-38),而英格兰和威尔士(1993)男性为10.8(10.0-11.6),女性为8.6(7.9-9.3)。我们的研究评估了一个时间段内的死亡率,因此不可能评论随时间的趋势。然而,人口老龄化可能导致未来中风死亡率大幅增加。
Background Most data for stroke mortality in sub-Saharan Africa are hospital based. We aimed to establish the contribution of cerebrovascular disease to all-cause mortality and cerebrovascular disease mortality rates in adults aged 15 years or more in one urban and two rural areas of Tanzania.Methods Regular censuses of the three surveillance populations consisting of 307 820 people (125 932 aged below 15 years and 181 888 aged 15 or more) were undertaken with prospective monitoring of all deaths arising in these populations between June 1, 1992 and May 31, 1995. Verbal autopsies were completed with relatives or carers of the deceased to assess. when possible. the cause of death.Findings During the 3-year observation period 11 975 deaths were recorded in the three surveillance areas, of which 7629 (64%) were in adults aged 15 years or more (4088 [54%] of these in men and 3541 [46%] in women). In the adults, 421 (5.5%) of the deaths were attributed to cerebrovascular disease, 225 (53%) of these in men and 196 (47%) in women. The yearly age-adjusted rates per 100 000 in the 15-64 year age group for the three project areas (urban, fairly prosperous rural, and poor rural, respectively) were 65 (95% CI 39-90), 44 (31-56), and 35 (22-48) for men. and 88 (48-128), 33 (22-43), and 27 (16-38) for women, as compared with the England and Wales (1993) rates of 10.8 (10.0-11.6) for men and 8.6 (7.9-9.3) for women.Interpretation We postulate that the high rates in Tanzania were due to untreated hypertension. Our study assessed mortality over a single time period and therefore it is not posible to comment on trends with time. However, ageing of the population is likely to lead to a very large increase in mortality from stroke in the future.