Synthesis of a heparinized poly(organophosphazene).
Synthesis of a heparinized poly(organophosphazene).
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DOI：
10.1016/0142-9612(82)90037-0
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发表时间：
1982-04
期刊：
影响因子：
14
通讯作者：
T. Neenan;H. Allcock
中科院分区：
文献类型：
--
作者：
T. Neenan;H. Allcock
介绍了一种新型抗血栓聚合物的合成方法。芳氧基取代聚磷腈的有限卤化，然后与三乙胺季铵化合成了一种能够与肝素钠形成聚电解质络合物的聚合物。给出了牛血的初步凝血试验结果。
The synthesis of a new potential anti-thrombogenic polymer is described. Limited halogenation of an aryloxysubstituted polyphosphazene, followed by quaternization with triethylamine yielded a polymer capable of forming polyelectrolyte complexes with sodium heparin. The results of preliminary clotting tests with bovine blood are presented.