Characteristics of two telephone screens for cognitive impairment
Characteristics of two telephone screens for cognitive impairment
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DOI：
10.1159/000048646
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发表时间：
2002-01-01
影响因子：
2.4
通讯作者：
Kaprio, J
中科院分区：
文献类型：
--
作者：
Järvenpää, T;Rinne, JO;Kaprio, J
我们研究了56名受试者，30名临床诊断为阿尔茨海默病(AD)的患者和26名健康对照，使用了两个认知障碍电话屏幕，一个被称为TELE的自我报告访谈和一个认知状态(TICS)的电话访谈。TELE对AD患者和健康对照组的敏感性和特异性分别为90.0%和88.5%，TICS分别为86.7%和88.5%。建立受试者操作者特征曲线时，TELE曲线下面积为96.0%(SE2.4%)，TICS为90.3%(SE4.2%)。TELE与简易智力状态检查(MMSE)的皮尔逊相关系数为0.87(p<；0.0001)，抽动障碍与MMSE的相关系数为0.86(p<；0.0001)。TELE与临床痴呆评定量表总分的相关系数分别为-0.71(p<；0.0001)和-0.75(p<；0.0001)。这些结果表明，这两种筛查都是区分AD患者和健康对照组的敏感而特异的工具，并且与面对面的认知功能测量有很强的相关性。版权所有(C)2002 S.Karger AG，巴塞尔。
We studied 56 subjects, 30 patients with a clinical diagnosis of Alzheimer's disease (AD) and 26 healthy controls, using two telephone screens for cognitive impairment, a self-report interview referred to as the TELE and the Telephone Interview for Cognitive Status (TICS). The sensitivity and specificity of the TELE to differentiate AD patients from healthy controls was 90.0 and 88.5% and those of the TICS were 86.7 and 88.5%, respectively. When receiver operator characteristic curves were constructed, the area under the curve for the TELE was 96.0% (SE 2.4%) and for the TICS 90.3% (SE 4.2%). Pearson's correlation between the TELE and the Mini-Mental State Examination (MMSE) was 0.87 (p < 0.0001) and between the TICS and the MMSE 0.86 (p < 0.0001). The correlation between the TELE and the sum of the boxes of the Clinical Dementia Rating scale (CDR-SB) was -0.71 (p < 0.0001) and -0.75 between the TICS and the CDR-SB (p < 0.0001). These results indicate that both screens are sensitive and specific instruments for differentiating AD patients from healthy controls and have a strong correlation with face-to-face measures of cognitive function. Copyright (C) 2002 S. Karger AG, Basel.