Effect of alpha-blockade on liver regeneration after carbon tetrachloride intoxication in the rat.

Effect of alpha-blockade on liver regeneration after carbon tetrachloride intoxication in the rat.
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α-阻断对大鼠四氯化碳中毒后肝再生的影响。

DOI:
10.1016/0006-2952(85)90195-9
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发表时间:
1985
影响因子:
5.8
通讯作者:
S. Kojo
S. Kojo
中科院分区:
医学2区
文献类型:
--
作者:
Y. Ochi;Y. Yumori;A. Morioka;K. Miura;I. Tsukamoto;S. Kojo

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材料与方法(?)-根据Huennekens等1171的方法,通过叶酸的催化氢化制备I_-四氢叶酸。15-3 HldUMP(14.8 Ci/mmole)和[6- 3 H]胸苷L(26 Ci/mmole)购自阿默舍姆。所有其他试剂均为分析级。Wistar雄性大鼠,st系,体重180-250 g。从静冈实验动物公司获得。(日本静冈)。Ccl组通过胃内管接受单剂量的0.5ml/100 g体重的Ccl在玉米油(1:1,v/v)中的溶液。苯巴比妥+CCl组[(PB+ CCl)组]在注射CCl前每日腹腔注射苯巴比妥8 mg/100 g体重,共3天。所有动物均可自由进食(市售饲料,MF颗粒,东方动物食品有限公司,日本大坂举行日本)和水。
Materials and methodsMaterials.(?)-I_-Tetrahydrofolic acid was prepared by catalytic hydrogenation of folic acid according to the method of Huennekens et al. 1171. 15-3HldUMP (14.8 Ci/mmole) and [6-3H] thymidine L (26 Ci/mmole) were purchased from Amersham. All other reagents were of analytical grade.Methods. Wistar male rats, strain st, weighing 180-250 g. were obtained from the Shizuoka Laboratory Animal Co.(Shizuoka, Japan). The Ccl, group recieved a single dose of 0.5 ml/100 g body wt of Ccl, in corn oil (1: 1, v/v) through an intragastric tube. The phenobarbital plus Ccl, group [the (PB+ CC&) group] received daily intraperitoneal injection of phenobarbital at a dose level of 8 mg/lOO g body wt for 3 days before the injection of CC&. All the animals had free access to food (commercial diet, MF pellets, Oriental Animal Foods Co., Osaka. Japan) and water.
DOI: 10.1016/s0021-9258(18)32512-2
发表时间: 1983-04
期刊: The Journal of biological chemistry
影响因子: --
作者:
C. Petropoulos;G. Andrews;T. Tamaoki;N. Fausto
通讯作者: C. Petropoulos;G. Andrews;T. Tamaoki;N. Fausto
用四氯化碳处理的大鼠肝脏中亚精胺 N-乙酰转移酶的特性及其在亚精胺转化为腐胺中的作用。
DOI: --
发表时间: 1981
期刊: The Journal of biological chemistry
影响因子: --
作者:
Matsui,I;Wiegand,L;Pegg,AE
通讯作者: Pegg,AE