Impaired facial recognition memory in aging and dementia.
Impaired facial recognition memory in aging and dementia.
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衰老和痴呆症中面部识别记忆受损。
DOI：
10.1097/00002093-199040100-00005
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发表时间：
1990
影响因子：
2.1
通讯作者：
Bartus,RT
中科院分区：
文献类型：
--
作者：
Flicker,C;Ferris,SH;Crook,T;Bartus,RT
年轻的正常人，老年正常人，早期和晚期可能的阿尔茨海默氏症型（DAT）的痴呆患者进行了面部识别记忆任务。一个连续的识别范式，其中受试者被指示识别重复的面孔，在一个正在进行的一系列的面孔呈现在视频监视器屏幕上。对数据的信号检测分析显示，DAT患者区分新面孔和重复面孔的能力明显受损。多次呈现的面孔只提高了早期DAT患者的识别准确率，但他们的学习速度比正常人慢。与年轻的正常人相比，老年正常人在识别记忆方面表现出轻微的缺陷。所有的老年受试者组表现出更自由的反应偏差比年轻的正常人，这消除了老年受试者的记忆任务表现受损的可能性，可以归因于一个更保守的考试策略。DAT患者表现出受损的识别，即使是在第二次呈现的脸紧接着第一次，这可能意味着，任务的性能也是敏感的DAT的视觉感知能力或心理速度的影响。
Young normals, aged normals, and patients with early and advanced probable dementia of the Alzheimer type (DAT) were administered a facial recognition memory task. A continuous recognition paradigm was used, in which subjects were instructed to identify the repeated faces in an ongoing series of faces presented on a video monitor screen. A signal detection analysis of the data revealed that the DAT patients were markedly impaired in their ability to discriminate between new and repeated faces. Multiple presentations of faces improved the recognition accuracy of the early DAT patients only, but their rate of learning was slower than that of the normal subjects. In comparison to the young normals, elderly normals exhibited a mild deficit in recognition memory. All of the elderly subject groups exhibited a more liberal response bias than the young normals, which eliminates the possibility that the impaired memory task performance of the aged subjects could be attributed to a more conservative test-taking strategy. The DAT patients exhibited impaired recognition even when the second presentation of a face immediately followed the first, which perhaps implies that task performance was also sensitive to the effect of DAT on visuoperceptual abilities or psychomotor speed.
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