Combine and Conquer: Double CTLA-4 and PD-1 Blockade Combined with Whole Tumor Antigen Vaccine Cooperate to Eradicate Tumors.
Combine and Conquer: Double CTLA-4 and PD-1 Blockade Combined with Whole Tumor Antigen Vaccine Cooperate to Eradicate Tumors.
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DOI：
10.1158/0008-5472.can-16-2868
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发表时间：
2016-12
期刊：
影响因子：
11.2
通讯作者：
K. Homicsko;Jaikumar Duraiswamy;M. Doucey;G. Coukos
中科院分区：
文献类型：
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作者：
K. Homicsko;Jaikumar Duraiswamy;M. Doucey;G. Coukos
访问癌症研究75周年纪念[时间轴][1].参见Duraiswamy等人的相关文章，[Cancer Res 2013;73：3591-603][2]。癌症劫持了正常炎症反应的正常调节途径。基本免疫检查点的失调几乎存在于所有
Visit the Cancer Research 75th Anniversary [timeline][1]. See related article by Duraiswamy et al., [Cancer Res 2013;73:3591–603][2] . Cancers hijack the normal regulatory pathways of normal inflammatory reactions. Dysregulation of fundamental immune checkpoints is present virtually in all