Biogeographic patterns in ocean microbes emerge in a neutral agent-based model
Biogeographic patterns in ocean microbes emerge in a neutral agent-based model
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DOI：
10.1126/science.1254421
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发表时间：
2014-09-12
期刊：
影响因子：
56.9
通讯作者：
Fredrick, Neil D.
中科院分区：
文献类型：
--
作者：
Hellweger, Ferdi L.;van Sebille, Erik;Fredrick, Neil D.
生态学和进化论中的一个关键问题是自然选择和中性进化在生物地理格局产生中的相对作用。我们通过在全球表层海洋环流模型中模拟100,000个拥有全部100万个碱基对基因组的海洋细菌细胞的分裂、突变和死亡来量化中性过程的作用。该模型运行了长达10万年，并使用BLAST(基本局部比对搜索工具)比对和元基因组学片段招募来分析输出。模拟显示了生物地理模式的产生和维持，其特点是不同的省份受到混合和邻居定期接管(合并)的影响，之后中性进化重建省份和模式重组。新出现的模式是实质性的(例如，北太平洋和中太平洋省份之间的DNA同源性低至99.5%)，表明微生物进化的速度快于洋流可以分散它们的速度。这种方法也可以用来探索环境选择。
A key question in ecology and evolution is the relative role of natural selection and neutral evolution in producing biogeographic patterns. We quantify the role of neutral processes by simulating division, mutation, and death of 100,000 individual marine bacteria cells with full 1 million-base-pair genomes in a global surface ocean circulation model. The model is run for up to 100,000 years and output is analyzed using BLAST (Basic Local Alignment Search Tool) alignment and metagenomics fragment recruitment. Simulations show the production and maintenance of biogeographic patterns, characterized by distinct provinces subject to mixing and periodic takeovers by neighbors (coalescence), after which neutral evolution reestablishes the province and the patterns reorganize. The emergent patterns are substantial (e. g., down to 99.5% DNA identity between North and Central Pacific provinces) and suggest that microbes evolve faster than ocean currents can disperse them. This approach can also be used to explore environmental selection.